Seeking Trip Advice, Gulf coast to Texas.

[misterprofessionality]

I've been considering the idea of a fairly big trip, maybe 2 or 3 days from Charleston, SC out to Texas, and i'm interested in taking advantage of either the Gulf Coast or an alternate route that will prove most enjoyable. Does anybody have any advice for riding in this direction during the Spring Season? landmarks to hit? Special roads (without going too far out of the way, I can only take 1 week off for this round trip, and want to bed down at least 2 or 3 nights at a final destination. )