Big Sur to Crater Lake...need route advice please!

[kvdv_imp]

Hi everyone!
My wife and I are looking forward to a great ride from Seattle down to Big Sur in September. I pretty much have the southbound route baked (we're riding the coast...woo hoo!), but I wanted us to head back north inland. That's where I need some help. I know that we'll want to swing through Crater Lake on our way home, and that per our schedule we have 4 days to get there upon leaving Big Sur. What I don't know is what the best route would be over those 4 days. By "best," my criteria is minimal or no interstate, great natural beauty as much as possible, decent lodging along the way (no camping - wife is along!), points of historical interest...that sort of thing.

So to any Cali natives or anyone else who knows the region well, if you had 4 days to ride from Big Sur to Crater Lake, what routes might you follow, or avoid, for that matter? Thanks so much!!