Warman wrote" I’ve been plagued by pain and comfort issues since returning to riding two years ago. First the seat limited me to only thirty minutes before I would get uncomfortable. Replaced the seat. Then the sciatic nerve pain from a tennis injury would start bothering me at about forty five minutes. My right leg just couldn’t stay in that position very long. "
Not sure how tall you are or if you have bio mechanical issues in play.
For me on longer trips I would end up with a pretty good cramp in my upper outside thigh/hip area once I got back on the bike after fueling/bathroom breaks etc.
I did the simple mod of putting on these foot pegs and that issue went away. I can't overstress what a difference they made even while on the bike. Multiple adjustment options depending on where you want the peg. I have them at the lowest neutral setting (no forward/aft bias).